He was treated with clindamycin alone as he had history of sulfonamide allergy. Based on the CT features and serology, diagnosis of cerebral toxoplasmosis was made. Toxoplasma serology revealed raised IgG antibody levels. Computed tomography scan of his brain showed irregular ring enhancing lesion in the right basal ganglia. A 30-year-old male known case of retroviral disease presented to Kasturba Medical College, India, with complaints of fever, headache and vomiting.
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Other alternative drugs used for the treatment of cerebral toxoplasmosis are clindamycin plus pyrimethamine and clarithromycin with pyrimethamine. Co-trimoxazole (trimethoprim plus sulfamethoxazole) is the most common drug used in India for the treatment of AIDS-associated cerebral toxoplasmosis. Toxoplasmosis is generally a late complication of HIV infection and usually occurs in patients with CD4 + T-cell counts below 200/μl. The authors recommend using clindamycin without pyrimethamine in resource poor settings and in patients who do not tolerate sulfa drugs.Ībstract = "Toxoplasmosis is caused by infection with the obligate intracellular parasite Toxoplasma gondii. The patient showed good clinical improvement within 48 hours and the lesion resolved completely within 3 weeks. After 21 days, repeat CT of brain was done which was normal. The patient was symptomatically better after 48 hours.
If you think you may have a medical emergency, call your physician or 911 immediately.Toxoplasmosis is caused by infection with the obligate intracellular parasite Toxoplasma gondii. By using this Site you agree to the following Terms and Conditions. We offer this Site AS IS and without any warranties. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site.
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